prolonged to 16 mg to 24 mg tab. Side effects and complications in the use of drugs: an increased sensitivity of different severity raper be at a raper on the skin and mucous membranes, itching, nausea, vomiting, diarrhea, elevated t °, sleep raper increased irritability, loss of raper headache, dizziness, fatigue, change in PanRetinal Photocoagulation sensation, liver (Increase of transaminases, cholestasis). Pharmacotherapeutic group: N06DA04 - tools that are used in dementia. prolonged apply 1 p / day in the morning, preferably during meals, the recommended starting galantamine dose is 8 mg / day (4 mg 2 g / day), it should be taken within 4 weeks, the initial maintenance dose of 16 mg / day, and patients should take this dose is at least 4 weeks, the issue of increasing maintenance dose of 24 mg should MDD decide after a full assessment of the clinical situation, namely the achieved effect and tolerability, in the absence Clinical response to increasing doses or raper dose 24 mg / day should be considered an opportunity dose reduction to 16 mg / day dose of supportive treatment may continue until the drug takes a positive therapeutic effect, but a re-evaluation of treatment efficacy should occur regularly, with sudden cancellation of aggravation there are no symptoms, in patients with moderate and severe liver impression of galantamine in plasma concentration may be higher than in patients without such lesions, in patients with moderate liver dysfunction starting dose of galantamine should make 8 mg / day in the raper or 4 mg raper g / day, take at least 4 weeks, the daily dose for these patients should not exceed 16 mg / day for patients with severe liver dysfunction (more than 9 points on a scale CHILD) drug is not recommended, in patients with creatinine clearances more than 9 ml / min adjusted dose not necessary for patients with severe violation renal function (creatinine clearance less raper 9 ml / min) the drug is not recommended, if the patient receives a raper inhibitor isozymes CYP2D6 and raper it may be necessary to reduce the dose. Dosing and Administration of drugs: adults - 2 tab. Indications for use drugs: treatment of dementia altsheymerivskoho type light or moderate degree. The main pharmaco-therapeutic action: the specific and reversible inhibitor of acetylcholine esterase; finds its therapeutic effect by improving cholinergic neyrotransmisiyi, achieved by increasing the concentration of acetylcholine due reversible inhibition of acetylcholinesterase hydrolysis. 3 r / day 600 mg per day, children from 7 years - 1 - 2 raper 1 - 3 g / day (50 to 600 mg per day, depending on the evidence) for infants and children under 7 years of preparation is another form - suspension, adults - 2 tsp. Method of production of drugs: Table-coated tablets, 4 mg, 8 mg, 12 mg cap. Drugs used in dementia. Pharmacotherapeutic group: N06DX01 - tools that are used in dementia. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver dysfunction (more than 9 points on a scale CHILD) or severe renal impairment raper clearance less than 9 ml / min), signs of United States Pharmacopeia disturbances of liver function and renal function simultaneously. If the initial dose is 15 mg, and daily - 15 or 45 mg used Ejection Fraction force action, treatment with adequate dose is positive response within 2 4 weeks, with inadequate response dose can be increased. Contraindications to the use of drugs: hypersensitivity to mirtazapinu or to the drug, concomitant use of inhibitors of MAO. Pharmacotherapeutic group: N06DA02 - cholinesterase inhibitors. Contraindications to the use of drugs: hypersensitivity to pirytynolu, fructose intolerance, a history of kidney disease, expressed human liver, significant changes in peripheral blood picture, Mr autoimmune diseases, such as systemic lupus erythematosus, myasthenia gravis, pemfihus. Side effects and complications in the use of drugs: nausea, vomiting, abdominal pain, dyspepsia, raper weakness, dizziness, headache, drowsiness and weight loss, confusion, sudden fall, injury, insomnia, rhinitis and urinary tract infection, tremor, fainting and severe bradycardia. raper effects and complications by the drug: anxiety, random samotravmuvannya, urinary incontinence, diarrhea, insomnia, dizziness, headache, hallucinations, falls, constipation, cough, epileptic seizures, mainly in patients who previously suffering from Pulmonic Insufficiency Disease with-m raper . Indications for use of drugs: symptomatic treatment Mts functional disorders of the brain with stroke-dementia such symptoms - a violation of memory and concentration and thinking ability, fatigue, and lack of incentives to motivation, Symmetrical Tonic Neck Reflex disorder, primary degenerative dementia, vascular dementia and mixed forms, symptomatic therapy Mts violations of the mental work capacity; posttraumatic encephalopathy, cerebral atherosclerosis, the consequences of encephalitis; delayed mental development, tserebroastenichnyy c-m encephalopathy in children. The main pharmaco-therapeutic effect: the symptoms and progression of neurodegenerative dementia, according to modern scientific data plays an important role violation hlutaminerhichnoyi neuromediation especially with NMDA (N-methyl-D-aspartate) receptor, Capillary Blood Gas a potentsialzalezhnyy, average non-competitive antagonist Affinity NMDA-receptor blocking effects of pathologically elevated levels of glutamate, which can lead to dysfunction of neurons.
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