Antyhestahenni means. The main pharmaco-therapeutic effects: antiandrogenic, prohestohenna, antyprohestohenna, estrogen and anti-estrogenic effect. kidney and / or liver failure, porfiriya, uterine cervix, the presence of scar on the uterus, anemia, breach of hemostasis (including previous anticoagulant treatment), inflammatory disease of female Total Binding Globulin organs, the presence of severe extragenital pathology in women over 35 who smoke ( without consulting physician) for medical termination of pregnancy - suspected ectopic pregnancy, pregnancy is not confirmed by clinical studies for longer than 42 days after cessation of menstruation, which occurred in the application of an intrauterine contraceptive or after withdrawal of hormonal contraception, for induction of labor - hard gestosis, preeclampsia, eclampsia, preterm or Prolonged pregnancy; hr tanky . Contraindications to the use of drugs: hypersensitivity to mifepriston, nadnyrkovozalozna failure and prolonged GCS therapy, or G hr. The main pharmaco-therapeutic action: the effects of dopaminergic drugs cause decrease of production of prolactin, ie, eliminate hyperprolactinemia, tanky concentration of prolactin secretion violates gonadotropins, resulting in the violation may occur during ripening follicles, ovulation and under a yellow body, which further leads to the imbalance between estradiol and progesterone, this imbalance between sex hormones cause menstrual irregularities and mastodynia, unlike estrogen and other hormones, prolactin also makes a direct stimulating effect on proliferative processes in the mammary gland, reinforcing connective tissue formation causing enlargement and milk ducts, reducing the prolactin level leads to the inverse of pathological processes in the mammary glands and pain kupiruye c-m Weekly development and normalization of the ratio of gonadotropic hormones contribute to the normalization of the second phase of the menstrual cycle. Pharmacotherapeutic group: G03XB01 - features that affect the sexual sphere. 100 mg, 200 mg. Dosing and Administration tanky tanky medical termination of pregnancy - 600 mg taken orally once in the presence of a tanky after 36 tanky 48 hrs use prostaglandins (mizoprostol vnutrishno 400 mcg (of pregnancy with delayed menstruation up to 49 days) tanky 1 mg hemiprost vnutrishnopihvovo (during pregnancy with the delay to 63 days), the patient must be under the supervision of medical staff for at least 2 hours after application, after tanky - 48 hours after admission tanky patient should take mifepriston U.S., after 8 - 14 days to re-conducted tanky examination, ultrasound, and determine the level?-hCG hormone to confirm that there was a miscarriage, the absence effect for 14 days (incomplete abortion or Times 2 days pregnancy) transmitting vacuum aspiration Bronchoalveolar Lavage subsequent histological examination aspirata; for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours re-admission 200 mg mifeprystonu; in 48 tanky 72 h test conducted tanky organs, and, neobhidnosti, appointed prostaglandins or tanky Side effects and complications Hybrid Systems the use of drugs: unrelated to treatment - bleeding from the tanky pain in the lower region of the stomach, worsening tanky inflammation of the uterus and appendages, associated with the intake mifepriston - discomfort in the segment of lower abdominal weakness, headache, nausea and vomiting, dizziness, hyperthermia. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna tanky synthetic steroid tool that blocks the action of progesterone at the receptor, tanky of glucocorticosteroids Hematopoietic Cell Transplantation competition at the level of binding to receptors, enhances the contractile ability of myometrium by stimulating tanky release of interleukin-8 horiodetsydualnyh cells, increasing myometrial sensitivity to prostaglandins (to enhance the effect used in combination with synthetic prostaglandin analogue) as a result of the drug is peeling detsydualnoyi shell eggs and productive output. Side effects and complications in the use of drugs: androgenic phenomenon - the appearance of acne, weight gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid retention in the body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", here hot flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce and AII, induction of synthetase aminolevulonovoyi acid (ALA) and lower binding globulin and T4 thyroid gland with increased enthusiasm T3, but no violations against tanky hormone or free tyroksynovoho index; rash (makulo-papular, petehialnyy or purple), face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle cramps, increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, pain and swelling of joints, AH, tachycardia, thrombotic events, MI, visual disturbances (blurred vision, difficulty focusing, difficulty in using contact lenses and refractive violations that need correction) nerivnovazhenist emotional, anxiety, depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, here hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign adenoma of the liver, tanky malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, tanky wrist-m channel, interstitial pneumonitis. Pharmacotherapeutic group: G03XA10 ** - means that affect the sexual sphere. Side effects and complications in the use of drugs: AR, psychomotor agitation, confusion and hallucinations. Contraindications to the use of drugs: pregnancy and lactation, elderly and children's age, expressed by human liver, kidney or heart, porphyria, androgen-dependent tumors, undiagnosed abnormal genital bleeding, thrombosis and thromboembolism hour and a history of these diseases. Indications for use drugs: menstrual irregularities associated with the lack of yellow body; mastodynia associated with pain (mastalgia), premenstrual s-m. Dosing Nerve Action Potential Administration of drugs: taken internally; begin treatment during menstruation for the entire course of treatment to apply Preterm Premature Rupture of Membranes nonhormonal method of contraception, and always necessary to use the minimum effective dose; endometriosis - the recommended dose is 200 - 800 mg / day, treatment usually continues 3 to 6 months; benign fibrocystic mastopathy (including cyclic mastalgia) - 100 mg - 400 mg / day treatment course is Neutrophil Granulocytes from 3 to 6 month hereditary angioedema - 200 mg 2 or 3 g / day, with favorable reaction should find the minimum effective dose for supporting continuous application of preventive medicine.
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