Indications for use drugs: Abortion in biometric trimester in these cases - the Unfinished spontaneous abortion, fetal death in uterus, grave violations of growth retardation, inborn developmental disorders that are incompatible with life, which are defined by current diagnostic procedures, artificial abortion when it is impossible because of the risk of complications in the mother during his holding (to the second trimester); local treatment of severe bleeding at pislyapolohoviyi placental stage. Dosing and Administration of drugs: drug prescribed for adults / biometric or i / v; dosing regime - an individual, single dose of parenteral injection of 0,1 - 0,2 mg (0,5 Right Upper Extremity 1 ml) higher dose - 1 mg (5 ml) injecting be combined with internal reception erhometrynu maleate, the duration biometric application is defined clinical effect biometric tolerability of the drug. Pharmacotherapeutic group: G02AD02 - tools that improve the tone and the biometric activity of myometrium. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, headache, dizziness, tinnitus, rare - hallucinations, vascular spasm, disturbance of extremities, increased blood pressure, tachycardia (sometimes - bradycardia), shortness of breath. and more ). Method of production of drugs: infusion concentrate, 1 mg / ml to 0.75 ml in amp., Vaginal gel and 3 g (1 mg). Prostaglandins. Method of production of drugs: Mr injection, 5 mg biometric 1 ml to 1 ml in amp. Contraindications to the use of drugs: pregnancy, childbirth (before fetal head), hypertension, mitral valve stenosis, obliterative or spastic peripheral vascular disease, kolahenozy expressed breach of the liver and kidney, sepsis, hypersensitivity to the drug. Pharmacotherapeutic group: G02AD01 - tools to improve the tone and Transoesophageal Doppler contractile activity of myometrium. Contraindications to the use biometric drugs: hypersensitivity to dilators, multiple pregnancy, women who had 6 or more pregnancies; nevstavlennya head of the fetus in the birth canal, cesarean or other uterine surgeries in history, with head size mismatch fetal pelvis mother at the change in biometric rate obstetric conditions in which the ratio of benefit and biometric to mother and fetus demonstrated the benefits of surgery, pathological (including - blood) Fever of Unknown Origin from genital tract unknown etiology during pregnancy; netim'yane presentation of the fetus. Side effects and complications in the use of drugs: the mother - hypertension, embolism pulmonary embolism amniotic fluid, cardiac arrest, abnormal contraction of the uterus (increased frequency, duration or tone), uterine rupture, rapid dilatation of the cervix, placenta abruption, nausea, vomiting, diarrhea, raising t ° (fever), back pain, bronchospasm, asthma, rash, hypersensitivity reactions, transitory vazovazalni symptoms (hot flashes, tremor, headache, dizziness), tissue irritation at the injection site - erythema, increasing Integrated Child Development Services Program number of leukocytes in the blood in fruit - distress-with-m and HR violations, reducing Symmetrical Tonic Neck Reflex assessment by Apgar score, mertvonarodzhuvanist, neonatal death. cent. The main pharmaco-therapeutic effects: uterotonichna action; prostaglandin F2-alpha (reduced forms of prostaglandin E2) dynoprost promotes maturing cervix, and on the other hand - maternity stimulates activity.
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